Mark Sculpher



Mark Sculpher is Professor of Health Economics and is Director of the Programme on Economic Evaluation and Health Technology Assessment. He is also Deputy Director of the Policy Research Unit in Economic Evaluation of Health and Care Interventions (EEPRU). He has been based at York University since 1997.

Between 1988 and 1997, he worked at the Health Economics Research Group at Brunel University; during 1998 he was a visitor in the Department of Clinical Epidemiology and Biostatistics at McMaster University in Canada.

Mark has worked on economic evaluations of a range of technologies including heart disease and various cancers.  He has also contributed to methods in the field, in particular relating to decision analytic modelling and handling uncertainty.  He has over 200 peer-reviewed publications and is a co-author of two major text books in the area: Methods for the economic evaluation of health care programmes (OUP, 2005 with Drummond, Torrance, O’Brien and Stoddart) and Decision modelling for health economic evaluation (OUP, 2006 with Briggs and Claxton).  

Mark was a member of the National Institute for Health and Care Excellence (NICE) Technology Appraisal Committee between 2004 and 2008, the NICE Public Health Interventions Advisory Committee between 2006 and 2009 and currently sits on the NICE Diagnostics Advisory Committee.  He chaired NICE's 2004 Task Group on methods guidance for economic evaluation and was a member of the Methods Working Party for the 2008 update of this guidance.  He was a member of the Commissioning Board for the UK NHS Health Technology Assessment Programme between 2007 and 2010, and the UK NIHR/Medical Research Council’s Methodology Panel between 2008 and 2011.  He is currently a member of the Policy Research Programme’s Commissioning Panel.  Mark is a National Institute for Health Research Senior Investigator and is a former President of the International Society of Pharmacoeconomics and Outcomes Research.



  • Decision analytic modelling, analysis of uncertainty and heterogeneity, economic evaluation and decision making

Research group(s)


  • National Institute for Health Research HTA Programme
  • National Institute for Health Research (NIHR)
    • Improving the quality of care of patients with angina and heart attack
    • Acupuncture for chronic pain and depression in primary care
    • Research Design Service – support in developing research by local clinicians and other researchers
  • Global Health
    • HIV modelling consortium (Bill and Melinda Gates Foundation)
    • Optimising Clinical Care in HIV (DFID
  • NIHR/Medical Research Council Methodology Research Programme
    • Methods for estimation of the NICE cost-effectiveness threshold
  • British Heart Foundation 
    • Cost-effectiveness of magnetic resonance imaging in coronary heart disease (CEMARC-2)


Mark Sculpher is part of the Thesis Advisory Group for:

External activities


Editorial duties

Recent Presentations

Staff Photo for Mark Sculpher

Contact details

Mark Sculpher
Centre for Health Economics